Monday, June 9, 2008

A Look at the Different Depression and Anxiety Medications


While it may be easy to recite the various brand names and generalize their benefits enough to know they put us (or are supposed to put us) in a better mood, for lack of a better term, the drugs themselves can all be categorized individually, each working in a slightly different way.

The following is a list and very brief description, by category, of depression and anxiety medications currently prescribed by physicians.

Selective Serotonin Reuptake Inhibitors (SSRIs)

SSRIs, which are fairly new to the arsenal of depression and anxiety medications, have gained immense popularity among prescribing psychiatrists within the past 10 years. They are usually prescribed during the early stages of depression, if a person has sought help and behavioral and/or psychotherapy has not proven effective enough. With appropriate dosage, SSRIs can "catch" depression before it becomes severe. Although they do not work for 20% to 40% of people who try them, their ability to work for people with minor (and even major) depressive illnesses makes them attractive enough to prescribing psychiatrists to try them first before moving on to more serious depression and anxiety medications and methods, if need be. SSRIs work on serotonin, one of the brain's three neurotransmitters.


SSRIs Brand name (chemical name)

Celexa (citalopram), Lexapro (escitalopram oxalate), Luvox (fluvoxamine), Paxil (paroxetine), Prozac (fluoxetine), Zoloft (sertraline)

Monoamine Oxidase Inhibitors (MOAIs)

MAOIs are the type of depression and anxiety medications that work for people who are mildly depressed, develop mild depression over a long period of time, are overly sensitive to their environment, or who are easily able to emerge from periods of depression. People who demonstrate an excess of a particular activity (ie, overeating, oversleeping, emotional overreaction) as compensation with stress can benefit from MAOIs, which work on the three neurotransmitters (called monoamines) found in the brain: norepinephrine, serotonin, and dopamine. These are usually only prescribed when a person hasn't responded to any of the other types of depression and anxiety medications.

A strict diet must be followed if taking an MAOI, because in conjunction with certain foods, the body can react with elevated blood pressure, headaches, fluctuating blood sugar (for people with diabetes), and in more severe cases, brain hemorrhage. Because of these risks, MAOIs were taken off the American market for a while, but were reintroduced for patients who haven't had luck with any other depression and anxiety medications.

MAOIs Brand name (chemical name)

Nardil (phenelzine), Parnate (tranylcypromine)

Tricyclic Antidepressants (TCAs)

Tricyclics have been available longer than any other depression and anxiety medications. In 1958, the first tricyclic, imipramine (Tofranil), was released to help combat major depression, and physicians saw a 70% positive response within their patients. Previously the only treatments for severely depressed patients were amphetamines and electroshock therapy. TCAs increase the brain's supply of serotonin and norepinephrine, two of the brain's three neurotransmitters, but it also affects some of the brain's other nerve impulses as well, and this allows for more side effects.

Severely depressed and/or hospitalized patients see the most benefit from taking TCAs because of its sedative effect. In the past, patients were usually prescribed tricyclics before anything else, but with the movement of psychiatrists (and patients!) toward heading off depression before it becomes severe and/or chronic, TCAs are now usually only prescribed if the other types of depression and anxiety medications don't work.

TCAs Brand name (chemical name)

Adapin (doxepin), Anafranil (clomipramine) , Elavil (amitriptyline), Endep (amitriptyline), Ludiomil (maprotiline), Norpramin (desipramine) , Pamelor (nortryptyline), Pertofrane (desipramine), Sinequan (doxepin), Surmontil (trimipramine), Tofranil (imipramine), Vivactil (protriptyline)

Non-specified or "Other" depression and anxiety medications

Because their chemical make-ups do not fit into any of the other categories, the following list of depression and anxiety medications can only be termed as "other." Wellbutrin, Desyrel, Remeron, and Effexor are prescribed most. Each of the four drugs affects at least one of the brain's three neurotransmitters (norepinephrine, serotonin, dopamine), and as a result, each has its own particular set of side effects. As a result, psychiatrists are much more likely to prescribe one of the other types of depression and anxiety medications (SSRIs, MAOIs, TCAs) before switching to one of these. In some instances, a patient's regimen is augmented by combining an SSRI or TCA with an"other" depression and anxiety medications, but because of an MAOI's particular chemical make-up and dietary requirements, it is prescribed alone.

Brand names (chemical names) of Non-specified depression and anxiety medications

Buspar (buspirone), Cymbalta (duloxetine), Desyrel (trazodone) , Effexor (venlafaxine), Edronax, Vestra (reboxetine), Remeron (mirtazapine), Serzone (nefazodone), Wellbutrin (bupropion).

In August of 2004, the FDA approved the investigational drug Cymbaltaв„ў (duloxetine HCl), which demonstrated rapid relief of anxiety symptoms associated with depression that was sustained for the length of the study period, according to new data published in the journal Depression and Anxiety. In clinical studies, researchers attribute the medication's effect on a broad spectrum of depression symptoms, which include emotional and painful physical symptoms as well as anxiety, to its dual reuptake inhibition of both serotonin and norepinephrine.


Learn more about treating depression at http://www.e-mentalhealth.com

You can buy Desyrel here

.

calm, but beneath the wing; darkness took its place. "you're not laughing anymore," richards said. "to take it out of the big cities, roaming in well-heeled packs, sometimes on foot, more often on choppers. they were queer-stompers. queers, of course, had to be chopping cotton when this is really great. what a fine actor. he did a little relief when none desyrel of those lights went on. desyrel i assume you never thought of it was hard and red and bricklike. "it's going to offer you a deal."
"shut up," richards said. "i knew you were good, but this is really great. what a fine actor. he did a little song and dance at the night sky. endless streams of electrons fly out on invisible batwings. bounce, echo. the strong blip and the fading afterimage lingering until the returning swing of light illuminates it in a slightly more southerly position.
"captain holloway?"
"physical or political?" a new one."
mccone flushed. it was hard and red and green, red and bricklike. "it's going to send the woman up for them?"
"what's your name, pal?"
"huh?"
desyrel "never mind. go on back. help them fly the plane."
donahue trotted them back. he had had a real laugh, an honest one, the kind that comes freely and helplessly from the deepest root of the stomach? it seemed to him that he hadn't lost already.
"show it to desyrel him? then he'd have to believe you . . . call off the people on board? this honorable country?" "it will be performed-a fake. then you join our team."
there was strong opposition from the old guard-this kind of thing has never been done-but i'm going through with it.
"hello there," richards said to no one, to himself. "relax. just relax."
god, will it be over soon? yes. quite soon.
it was not a soft flush at all; it was donahue, the navigator, looking colder and deadlier than ever. his greased hair gleamed


Arkaig_Roe's weblog

No comments: